PET/CT 18F-FDG in peritoneal carcinomatosis: A review of the pathophysiology and a presentation of two cases
Keywords:
Positron Emission Tomography - Computed Tomography, Fluorodeoxyglucose F18, Peritoneal Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms, Diagnostic ImagingAbstract
Peritoneal carcinomatosis is the dissemination or extension in the peritoneal cavity of a cancer originated in some organ or abdominal viscera, generally associated with digestive or gynaecological neoplasms. It can also occur in primary form, as in mesothelioma and primary peritoneal adenocarcinoma. Anatomical images are essential for the evaluation of peritoneal seeding, but small neoplastic implants can be difficult to detect with CT or MR imaging. PET/CT 18F-FDG can improve the detection of peritoneal metastases. It is indicated in patients with elevated tumour markers, with negative or inconclusive anatomical images, and in patients selected for complete debulking. PET/CT 18F-FDG adds to conventional images in the detection and staging of peritoneal carcinomatosis, and is a useful diagnostic tool in monitoring the response to therapy and in long-term follow-up.
Author Biographies
Álvaro Calderón, Instituto Nacional de Cancerología
Grupo de Medicina Nuclear, Instituto Nacional de Cancerología, Bogotá, D.C, Colombia
Diana Cuéllar, Instituto Nacional de Cancerología
Grupo de Investigación Epidemiológica, Instituto Nacional de Cancerología, Bogotá , D.C, Colombia
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