Uterine smooth muscle tumor of uncertain malignant potential (STUMP): case report and literature review
DOI:
https://doi.org/10.35509/01239015.862Keywords:
Uterine neoplasms, muscle, smooth, myometrium, leiomyosarcomaAbstract
Myometrial smooth muscle neoplasms are the most common gynecologic tumors with a prevalence of 70-80% at age 50. Among women undergoing hysterectomy or myomectomy for a suspected diagnosis of leiomyoma, 0.01% receive a diagnosis of STUMP. Clinically, the average age of presentation is between 41-48 years. Tumors ranging from 3 to 30 cm have been described. Signs and symptoms are similar to leiomyomas, such as abnormal uterine bleeding, anemia, dysmenorrhea, pelvic pain, pelvic mass, infertility or other types of pain secondary to compression of adjacent organs. Due to the limited literature available, there is no definite management consensus, and treatment and follow-up options are limited to observational studies. The standard treatment is total hysterectomy with or without bilateral salpingo-oophorectomy; if fertility has already been completed, there is no role for adjuvant hormonal therapy or chemotherapy. The overall 5-year survival is 92-100%. A case of a 31-year-old woman with STUMP is presented.
Author Biographies
Oscar Fernando Serrano-Ortiz, Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
1. Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
2. Unidad de Ginecología Oncológica, Hospital Militar Central, Bogotá, D.C., Colombia.
Jairo Alonso Hernández-Gómez, Fellow Unidad Funcional Ginecología, Instituto Nacional de Cancerología, Bogotá, D.C., Colombia.
3. Fellow Unidad Funcional Ginecología, Instituto Nacional de Cancerología, Bogotá, D.C., Colombia.
Diana Jimena Santana, Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
1. Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
Carlos Fernando Bonilla, Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
1. Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
Amaury García-Burgos, Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
1. Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
Joaquín Luna, Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
1. Departamento de Ginecología Oncológica, Clínica Colsanitas, Bogotá, D.C., Colombia.
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