Subcutaneous panniculitis-likeT-cell lymphoma and haemophagocytic syndrome
Keywords:
panniculitis, lymphoma, T-cell, cutaneous, histiocytosisAbstract
We report the case of a 57-year-old Colombian male with a 3-month history of subcutaneous nodular eruption confined to a small area located in the abdomen and inguinal area accompanied by secondary ulceration, pancytopenia and fever. Histopathological examination revealed an atypical lymphoid cell localized localised to the panniculus. These cells were identified as T-cells by immunohistochemistry; there was associated karyorrhexis, angiocentric infiltration and fat necrosis consistent with a subcutaneous T-cell lymphoma, a rare subset of peripheral T-cell lymphoma accompanied by haemophagocytic syndrome. Haemophagocytosis was present in the panniculus and bone marrow, no tumor being evident outside the subcutaneous tissue. The patient presented a poor response to chemotherapeutical treatment and multiple infectious complications during his hospitalization.
Author Biographies
Andrés Felipe Cardona, Instituto Nacional de Cancerología E.S.E.
Instituto Nacional de Cancerología E.S.E.
Grupo Oncología Clínica
Bogotá, D.C.
Colombia
Ludovic Reveiz, Grupo Colombiano de la Colaboración Cochrane
Grupo Colombiano de la Colaboración Cochrane
Myriam Rodríguez, Instituto Nacional de Cancerología E.S.E.
Instituto Nacional de Cancerología E.S.E.
Grupo Hematología y Trasplante de Medula Ósea
Bogotá, D.C
Colombia
Pedro Luis Ramos, Instituto Nacional de Cancerología E.S.E.
Instituto Nacional de Cancerología E.S.E.
Grupo Oncología Clínica
Bogotá, D.C.
Colombia
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