Utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) with rapid on-site evaluation (ROSE) for the molecular classification of progressive breast cancer
DOI:
https://doi.org/10.35509/01239015.65Keywords:
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), Breast cancer, Rapid on-site evaluation (ROSE)Abstract
Evidence of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS- TBNA) in extrathoracic malignancy is limited but emergent. The technique plays a vital role in the diagnosis of mediastinal lesions, staging, and restaging of lung cancer. Its usefulness for the evaluation and molecular classification of progressive breast cancer is described in 7 patients. Stations 7, 11L, and 11R were punctured. Cellblocks, immunohistochemistry and digital analysis were developed in 100% of the cases for molecular classification. This procedure requires multidisciplinary evaluation, image analysis, and evaluation of the general condition of the patient, as well as the risks and benefits. Additionally, it is essential teamwork with a pathology group that performs the rapid on-site evaluation (ROSE), in order to ensure the quality of the samples and molecular characterization.
Author Biographies
Liliana Fernández-Trujillo, Fundación Valle del Lili University Hospital - Universidad Icesi
Department of Internal Medicine, Pulmonology Service, Interventional Pulmonology, Fundación Valle del Lili University Hospital, Cali, Colombia
Faculty of Health Science, Universidad Icesi, Cali, Colombia
Carl Sebastián Leib, Fundación Valle del Lili University Hospital
Clinical Research Center, Fundación Valle del Lili University Hospital, Cali, Colombia
Marisol Aguirre-Rojas, Universidad Icesi - Fundación Valle del Lili University Hospital
Faculty of Health Science, Universidad Icesi, Cali, Colombia
Department of Pathology and Laboratory Medicine, Fundación Valle del Lili University Hospital, Cali, Colombia
Luz Fernanda Sua, Universidad Icesi - Fundación Valle del Lili University Hospital
Faculty of Health Science, Universidad Icesi, Cali, Colombia
Department of Pathology and Laboratory Medicine, Fundación Valle del Lili University Hospital, Cali, Colombia
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