A Histopathological and Immunohistochemical Case Study of a Primary Primitive Neuroectodermal Bladder Tumor
Keywords:
Urinary bladder neoplasms, immunohistochemistry, histologyAbstract
A primary primitive neuroectodermal bladder tumor, which occurs among patients over 50, is not common. It is an extremely malignant, advanced regional disease that spreads rapidly and is usually lethal. Diagnosis requires ruling out other neoplasms; thus making immunohistochemical and cytogenetic studies indispensable. We report on a case treated at the National Cancer Institute of Colombia. Histopathological studies revealed the presence of a primary primitive neuroectodermal bladder tumor and ruled out differential diagnosis of carcinoma and bladder lymphoma. The immunohistochemical results confirmed neuroectodermal tumor origin and ruled out epitelial neoplasms and hematolymphoids which frequently occur in the bladder. The clinical evolution coincides with that of the literature on short term fatal outcomes.
Author Biographies
Alfredo Ernesto Romero Rojas, Instituto Nacional de Cancerología Bogotá
Instituto Nacional de Cancerología Bogotá, Colombia.
Diana Marcela Hernández Walteros, Instituto Nacional de Cancerología Bogotá
Instituto Nacional de Cancerología Bogotá, Colombia.
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