Prevalence of Cytological and Histological Cervical Uterine Abnormalities in a Group of Women in Bogotá, Colombia
Keywords:
Cervical intraepithelial neoplasia, prevalence, epidemiology, mass screeningAbstract
Objective: To describe the prevalence of cytological abnormalities and neoplasias in a group of women from Bogotá, Colombia.
Methods: A descriptive analysis was done among women attended health services in a low-resource area of Bogotá. All women had history of sexual onset, aged 25 to 59 years, and were investigated with conventional cytology.
Results: 4,957 cases were analyzed. The average age was 39.2 years. In total 69.1% of pap smears were negative, 24.7% reported ASC-US, 4.3% LSIL, 1.2% HSIL, and 0.1% invasive cancer. 762 biopsies were done (48.29% negative and 49,08% neoplasic changes). The global prevalence of intraepithelial neoplasias and carcinoma was 7.54%. The prevalence of CIN 2 and CIN 3 was 1.3% (0.4% y 0.9%). Two invasive carcinomas were detected (0.04%).
Conclusions: The prevalence of cytological abnormalities was unusually high. Histological abnormalities were investigated through three different screening methods representing highly reliable data. The prevalence of HSIL (CIN II and CIN III) and invasive cancer observed is higher than previous reports from other countries.
Author Biographies
Mauricio González, Instituto Nacional de Cancerología
Grupo de Investigación Clínica, Instituto Nacional de Cancerología. Bogotá, Colombia.
Raúl Murillo, Instituto Nacional de Cancerología
Subdirección de Investigaciones, Vigilancia Epidemiológica, Promoción y Prevención, Instituto Nacional de Cancerología. Bogotá, Colombia.
Elkin Osorio, Secretaría Distrital de Salud
Laboratorio de Salud Pública, Secretaría Distrital de Salud. Bogotá, Colombia.
Óscar Gamboa, Instituto Nacional de Cancerología
Subdirección de Investigaciones, Vigilancia Epidemiológica, Promoción y Prevención, Instituto Nacional de Cancerología. Bogotá, Colombia.
Jaime Ardila, Instituto Nacional de Cancerología
Subdirección de Investigaciones, Vigilancia Epidemiológica, Promoción y Prevención, Instituto Nacional de Cancerología. Bogotá, Colombia.
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