Isolated Limb Perfusion. Initial Experience at the National Cancer Institute of Colombia, 2007-2008
Keywords:
Chemotherapy, neoplams, regional perfusion, sarcomas, melanoma, limb salvageAbstract
Objective: To describe the initial experience of isolated limb perfusion at the National Cancer Institute.
Methods: Pathology and response to intervention was documented in the cases of 13 patients taken from years 2007 to 2008.
Results: Limb salvage was 76%; local complications, 16%. Five patients (41.7%) had partial response; two more (16.7%), disease progression. No patients had complete clinical response.
Conclusions: Isolated limb perfusion provides a good alternative for treating melanoma and advanced sarcomas in limbs; possibly sparing them from amputation. Due to the number of patients included in this article, and to the need to establish more solid conclusions, it is necessary to carry out closer patient follow-up by setting up a prospective research project whose results will establish type of response, disease free interval, overall survival and a quality-of-life scale for patients who receive this kind of treatment.
Author Biographies
Carlos Duarte, Instituto Nacional de Cancerología
Grupo de Cirugía Oncológica, Instituto Nacional de Cancerología, Bogotá D.C., Colombia
Mauricio García, Instituto Nacional de Cancerología
Grupo de Cirugía Oncológica, Instituto Nacional de Cancerología, Bogotá D.C., Colombia
Carlos Lehmann, Instituto Nacional de Cancerología
Grupo de Cirugía de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá D.C. Colombia
Ricardo Sánchez, Instituto Nacional de Cancerología
Grupo de Investigación Clínica, Instituto Nacional de Cancerología, Bogotá D.C., Colombia
Jorge Manrique, Instituto Nacional de Cancerología
Grupo de Investigación Clínica, Instituto Nacional de Cancerología, Bogotá D.C., Colombia
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