Major amputations in oncological surgery: A retrospective analysis of 80 cases in the Instituto Nacional de Cancerología
Keywords:
MeSH, Neoplasm, Cancer;, Amputation, ExtremitiesAbstract
Objective: To describe the epidemiological, clinical and treatment characteristics of patients with soft tissue tumours, melanoma, and squamous cell carcinomas of the Breast and Soft Tissue Department of the Instituto Nacional de Cancerologìa, who had major limb amputations between the years 1998 and 2008.
Methods: a review was made of the clinical records of 80 patients in whom a major limb amputation was performed between January 1998 and December 2008 in the Breast and Soft Tissue Department of the Instituto Nacional de Cancerologìa.
Results: Of the 80 patients studied, 24 had a classic hemipelvectomy, 22 with hip disarticulation, 19 with interscapular-thoracic disarticulation, 8 with hemi-hemipelvectomy, and 7 with shoulder disarticulation. The diagnoses, in order of frequency were: soft tissue sarcomas, 72.5%; squamous cell carcinomas, 21.2%; and melanoma, 6.2%. The intention of the surgery was curative in 50% of the cases. There was a greater number of complications in the patients where the intention of the surgery was palliative, with a significant significance only for necrosis of flaps (22.5% vs. 5% p=.02). The one-year survival in the patients with intention to cure surgery was 67.5% vs. 42.5% for palliative surgery (p=.038).
Conclusions: in patients with tumours proximal to the limbs, where preservative surgery is impossible, major amputations continue to be a valid therapeutic option, despite its high rate of complications.
Author Biographies
Sandra Díaz, Instituto Nacional de Cancerología
Grupo de Seno y Tumores de Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Carlos Lehmann, Instituto Nacional de Cancerología
Grupo de Investigación Clínica Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Licet Villamizar, Instituto Nacional de Cancerología
Grupo de Investigación Clínica Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Javier Ángel, Instituto Nacional de Cancerología
Grupo de Seno y Tumores de Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Dimelza Osorio, Instituto Nacional de Cancerología
Grupo de Investigación Clínica Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Alejandra Sánchez, Liga Contra el Cáncer
Cirujano de Seno y Tumores de Tejidos Blandos, Liga Contra el Cáncer, Seccional Risaralda, Manizales, Colombia
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