I-131 SPECT /CT in differentiated thyroid cancer

Authors

  • Augusto Llamas Olier Instituto Nacional de Cancerología
  • Enrique Cadena Instituto Nacional de Cancerología

Keywords:

Emission-computed single-photon tomography, Emission-computed tomography, Thyroid neoplams, I-131, Fusion image
Abstract Authors References How to Cite

Abstract

The frequency of thyroid cancer has increased over the past twenty years probably due to the use of high-resolution diagnostic studies. Treatment is based upon thyroidectomy plus radioactive iodine remnant ablation (RRA) and suppressive therapy with sodium levothyroxine, and follow-up with thyroglobulin and high-resolution ultrasound. RRA is followed by a planar whole-body scan oftentimes unable to provide exact uptake localization. Single-photon emission computed tomography/computed tomography (SPECT/CT) has emerged as an imaging complement to acquire fused images that can provide anatomic localization of radioactive sites. We used it to clarify the location of an avid lesion after administering 200 mCi of I-131 to a female patient as part of her treatment

Author Biographies

Augusto Llamas Olier, Instituto Nacional de Cancerología

Grupo de Medicina Nuclear, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia

Enrique Cadena, Instituto Nacional de Cancerología

Grupo de Cabeza y Cuello, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Unidad de Otorrinolaringología, Universidad Nacional de Colombia, Bogotá, D. C., Colombia

References

Wong KK, Zarzhevsky N, Cahill JM, Frey KA, Avram AM. Incremental value of diagnostic 131I SPECT/CT fusion imaging in the evaluation of differentiated thyroid carcinoma. AJR. 1998; 191:1785- 94.

https://doi.org/10.2214/AJR.08.1218

Garavito G, Llamas A, Cadena E, De Los Reyes CA, Hurtado G, Rojas L, et al. Manejo multidisciplinario del cáncer diferenciado de tiroides en el Instituto Nacional de Cancerología. Rev Colomb Cancerol. 2010;14:65-77.

https://doi.org/10.1016/S0123-9015(10)70100-1

Roarke MC, Nguyen BD, Pockaj BA. Applications of SPECT/CT in nuclear radiology. Am J Roentgenol. 2008;191:135-50.

https://doi.org/10.2214/AJR.07.3564

Llamas A, Cadena E, De Los Reyes CA, Bermeo G. Linfo gammagrafía con SPECT/CT en neoplasias cutáneas de cabeza y cuello. Rev Colomb Cancerol. 2012;16:65-71.

https://doi.org/10.1016/S0123-9015(12)70032-X

Sherman SI. Thyroid carcinoma. Lancet. 2003;361:501-11.

https://doi.org/10.1016/S0140-6736(03)12488-9

Delbeke D, Schöder H, Martin WH, Wahl RL. Hybrid imaging (SPECT/CT and PET/CT): improving therapeutic decisions. Semin Nucl Med. 2009;39:308-40.

https://doi.org/10.1053/j.semnuclmed.2009.03.002

Yamamoto Y, Nishiyama Y, Monden T, Matsumura Y, Satoh K, Ohkawa M. Clinical usefulness of fusion of I-131 SPECT and CT images in patients with differentiated thyroid carcinoma. J Nucl Med. 2003;44:1905-10.

Ruf J, Lehmkuhl L, Bertram H, Sandrock D, Amthauer H, Humplik B, et al. Impact of SPECT and integra ted low-dose CT after radioiodine therapy on the management of patients with thyroid carcinoma. Nucl Med Commun. 2004;25:1177- 82.

https://doi.org/10.1097/00006231-200412000-00004

Tharp K, Israel O, Hausmann J, Bettman L, Martin WH, Daitzchman M, et al. Impact of 131I-SPECT/CT images obtained with an integrated system in the follow-up of patients with thyroid carcinoma. Eur J Nucl Med Mol Imaging 2004;31: 1435-42.

https://doi.org/10.1007/s00259-004-1565-2

Aide N, Heutte N, Rame JP, Rousseau E, Loiseau C, Henry-Amar M, et al. Clinical relevance of single-photon emission computed tomography/computed tomography of the neck and thorax in postablation I-131 scintigraphy for thyroid cancer. J Clin Endocrinol Metab 2009; 94:2075-84.

https://doi.org/10.1210/jc.2008-2313

Chen L, Luo Q, Shen Y, Yu Y, Yuan Z, Lu H, et al. Incremental value of 131I SPECT/CT in the management of patients with differentiated thyroid carcinoma. J Nucl Med 2008;49:1952-7.

https://doi.org/10.2967/jnumed.108.052399

Kohlfuerst S, Igerc I, Lobnig M, Gallowitsch HJ, Gómez-Segovia I, Matschnig S, et al. Posttherapeutic 131I SPECT-CT offers high diagnostic accuracy when the findings on conventional planar imaging are inconclusive and allows a tailored patient treatment regimen. Eur J Nucl Med Mol Imaging. 2009;36: 886-93.

How to Cite

[1]
Llamas Olier, A. and Cadena, .E. 2013. I-131 SPECT /CT in differentiated thyroid cancer. Revista Colombiana de Cancerología. 17, 3 (Sep. 2013), 122–125.

Downloads

Download data is not yet available.

Downloads

Published

2013-09-01

Issue

Vol. 17 No. 3 (2013)

Section

Imágenes en Oncología

License

Todos los derechos reservados.