Lipomatous hypertrophy of the interatrial septum. A case report

Authors

  • Fredy Rolando Salazar Heredia Programa de Patología Anatómica y Clínica, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D. C., Colombia
  • Patricia López Departamento de Patología, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
  • Juan Carlos Mejía Departamento de Patología, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia

DOI:

https://doi.org/10.35509/01239015.347

Keywords:

Pathology, Diagnosis, Heart Tumors., Hypertrophy, atrial septum

Abstract

Lipomatous Hypertrophy of the Interatrial Septum (LHIS) is a rare and benign cardiac entity that is characterized by the accumulation of adipose tissue within some segments of the interatrial septum. Patients are generally asymptomatic, and these lesions are discovered incidentally by imaging studies performed for other reasons, or in the context of an autopsy. In these patients, there have been described cases of sudden death due to disturbance of the heart rhythm. The differential diagnosis of LHIS mainly includes cardiac tumors. Here we present a case of a 61-year-old patient in whom, after a cardiac magnetic resonance study performed for an abnormal heart rhythm, it was documented a mass in the atrial septum. The patient was taken to surgery, and the histopathological study of the lesion confirmed the diagnosis. We conduct a review of the clinical and pathological characteristics of LHIS.

 

References

Prior JT. Lipomatous hypertrophy of cardiac interatrial septum. Arch Pathol. 1964;78:11-5

Nadra I, Dawson D, Schmitz SA, Punjabi PP, Nihoyannopoulos P. Lipomatous hypertrophy of the interatrial septum: a commonly misdiagnosed mass often leading to unnecessary cardiac surgery. Heart. 2004;90:e66. https://doi.org/10.1136/hrt.2004.045930

Hejna P, Janík M. Lipomatous hypertrophy of the interatrial septum: a possibly neglected cause of sudden cardiac death. Forensic Sci Med Pathol. 2014;10:119-21. https://doi.org/10.1007/s12024-013-9480-0

Miraglia E, Visconti B, Bianchini D, Calvieri S, Giustini S. An uncommon association between lipomatous hypertrophy of the interatrial septum (LHIS) and Dercum’s disease. Eur J Dermatol. 2013;23:406-7. https://doi.org/10.1684/ejd.2013.2016

O’Connor S, Recavarren R, Nichols L, Parwani AV. Lipomatous hypertrophy of the interatrial septum: an overview. Arch Pathol Lab Med. 2006;130:397-9.

Heyer CM, Kagel T, Lemburg SP, Bauer TT, Nicolas V. Lipomatous hypertrophy of the interatrial septum: a prospective study of incidence imaging findings, and clinical symptoms. Chest. 2003;124:2068-73. https://doi.org/10.1378/chest.124.6.2068

Xanthos T, Giannakopoulos N, Papadimitriou L. Lipomatous hypertrophy of the interatrial septum: a pathological and clinical approach. Int J Cardiol. 2007;121:4-8. https://doi.org/10.1016/j.ijcard.2006.11.150

Tutar E, Çiftçi O, Fitoz S, Kendirli T, Ödek Ç, Uçar T, et al. Lipomatous hypertrophy of the interatrial septum in a child with atrial tachycardia. Pediatr Int. 2016;58:523-5. https://doi.org/10.1111/ped.12917

Laura DM, Donnino R, Kim EE, Benenstein R, Freedberg RS, Saric M. Lipomatous atrial septal hypertrophy: a review of its anatomy, pathophysiology, multimodality imaging, and relevance to percutaneous interventions. J Am Soc Echocardiogr. 2016;29:717-23. https://doi.org/10.1016/j.echo.2016.04.014

Escobar C, Jaramillo M, Tenorio L, Molina C, Saldarriaga M, Arango A. Ecocardiografía transesofágica en el estudio de pacientes con eventos cerebrovasculares en quienes se sospecha origen cardiovascular embólico. Rev Col Cardiol. 2003;10:199-204.

Miller DV, Tazelaar HD. Cardiovascular pseudoneoplasms. Arch Pathol Lab Med. 2010;134:362-8.

Bois M, Bois JP, Anavekar NS, Oliveira AM, Maleszewski JJ. Benign lipomatous masses of the heart: a comprehensive series of 47 cases with cytogenetic evaluation. Hum Pathol. 2014;45:1859-65. https://doi.org/10.1016/j.humpath.2014.05.003

Rob D, Kuchynka P, Palecek T, Cerny V, Masek M, Vitkova I, et al. A rare case of regressively changed lipomatous hypertrophy of the interatrial septum presenting with anemia and recurrent fever. Cardiovasc Pathol. 2016;25:161-4. https://doi.org/10.1016/j.carpath.2015.09.002

Calé R, Andrade MJ, Canada M, Hernandez ER, Lima S, Abecasis M, et al. Lipomatous hypertrophy of the interatrial septum: report of two cases where histological examination and surgical intervention were unavoidable. Eur J Echocardiogr. 2009;10:876-9. https://doi.org/10.1093/ejechocard/jep080

Bielicki G, Lukaszewski M, Kosiorowska K, Jakubaszko J, Nowicki R, Jasinski M. Lipomatous hypertrophy of the atrial septum - a benign heart anomaly causing unexpected surgical problems: a case report. BMC Cardiovasc Disord. 2018;18:152. https://doi.org/10.1186/s12872-018-0892-3

How to Cite

[1]
Salazar Heredia, F.R. et al. 2020. Lipomatous hypertrophy of the interatrial septum. A case report. Revista Colombiana de Cancerología. 24, 2 (May 2020), 92–95. DOI:https://doi.org/10.35509/01239015.347.

Downloads

Download data is not yet available.

Published

2020-05-26

Issue

Section

Reportes de caso
Crossref Cited-by logo