SPECT/CT for lymphatic mapping of sentinel nodes in carcinoma of oropharynx
Keywords:
Emission-computed single-photon tomography, Emission-computed tomography, Sentinel lymph node biopsy, Carcinoma, NeckdissectionAbstract
The diagnosis of oropharyngeal cancer is difficult because the initial symptoms are unusual, is evident some times when the patient has a large tumor. To realize appropriate treatment is essential to know if existing nodal infiltration, more even when the standard management is surgical resection, in the last decade is robot-assisted transoral surgery. The microscopic positive lymph node depends on the level of infiltration of the tumor and may be up to 40%. The lymphatic mapping of sentinel nodes is make by lymphoscintigraphy, its accuracy improves when the images are obtained with SPECT/CT. Recently, we did this study in a patient with a tumor at the base of tongue, confirming the presence of a sentinel node of IIA level. The main advantage was the anatomical accuracy when we make fusion of images with SPECT/CT.
Author Biographies
Enrique Cadena, Instituto Nacional de Cancerología
Cirugía de Cabeza y Cuello, Instituto Nacional de Cancerología, Bogotá D. C., Colombia
Unidad Otorrinolaringología, Universidad Nacional de Colombia, Bogotá D. C., Colombia
Unidad de Otorrinolaringología, Cirugía de Cabeza y Cuello, Cirugía Robótica, CiruRobótica, Clínica de Marly, Bogotá D.C., Colombia
Carmen Amelia de los Reyes, Instituto Nacional de Cancerología
Grupo de Medicina Nuclear, Instituto Nacional de Cancerología, Bogotá D. C., Colombia
References
Ferlay J, Shin HR, Bray F, et al. GLOBOCAN 2008 v2.0, cancer incidence and mortality worldwide: IARC cancerbase No. 10 [Internet]. Lyon (France): International Agency for Research on Cancer; 2010. Available at: http://globocan.iarc.fr. Accessed August 30, 2012.
Instituto Nacional de Cancerología. E.S.E (INC) Anuario estadístico 2009. Bogotá: INC; 2011.
Hashibe M, Brennan P, Chuang SC, Boccia S, Castellsague X, Chen C, et al. Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiol Biomarkers Prev. 2009;18(2):541-50.
https://doi.org/10.1158/1055-9965.EPI-08-0347
Sturgis EM, Ang KK. The epidemic of HPV-associated oropharyngeal cancer is here- is it time to change our treatment paradigms? J NatlComprCancNetw. 2011;9:665-73.
https://doi.org/10.6004/jnccn.2011.0055
Hashib M, Sturgis EM. Epidemiology of Oral-Cavity and Orop- haryngeal Carcinomas Controlling a Tobacco Epidemic While a Human Papillomavirus Epidemic Emerges. Otolaryngol Clin N Am. 2013;46:507-20.
https://doi.org/10.1016/j.otc.2013.05.001
Cohen MA, Weinstein GS, O'Malley BW Jr, Feldman M, Quon H. Transoral robotic surgery and human papillomavirus status: oncologic results. HEAD & NECK-DOI 10.1002/hed April 2011.
https://doi.org/10.1002/hed.21500
Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst. 2000;92:709-20.
Weinstein GS, Quon H, OM ́alley Jr BW, Kim GG, Cohen MA. Selective Neck Dissection and Deintensified Postoperative Radiation and Chemotherapy for Oropharyngeal Cancer: A Subset Analysis of the University of Pennsylvania Transoral Robotic Surgery Trial. Laryngoscope. 2010;120:1749-55.
https://doi.org/10.1002/lary.21021
Vermeeren L, Klop WMC, van den Brekel MWM, Balm AJM, Nleweg OE, Valdés-Olmos RA. Sentinel node detection in head and neck malignancies: innovations in radioguidedsurgery. J Oncol. 2009;(681746):10,
https://doi.org/10.1155/2009/681746
Cadena E, Calderón A, Bermeo G. SPECT/CT para mapeo linfático en disección superselectiva de cuello de carcinoma escamocelular de lengua. RevColombCancerol. 2013;17(2): 86-90.
Llamas A, Cadena E, de los Reyes CA, Bermeo G. Linfogammagrafía con SPECT/CT en neoplasias cutáneas de cabeza y cuello. RevColombCancerol. 2012;16(1):234-9.
https://doi.org/10.1016/S0123-9015(12)70032-X
Coughlin A, Resto VA. Oral cavity squamous cell carcinoma and the clinically N0 neck: The past, present, and future of sentinel lymph node biopsy. CurrOncol Rep. 2010;12(2):129-35. virus and a subset of head and neck cancers. J Natl Cancer Inst. 2000;92:709-20.
https://doi.org/10.1007/s11912-010-0090-7
Keski-Säntti H, Kontio R, Törnwall J, Leivo I, Mätzke S, Suominen S, et al. Sentinel lymph node biopsy or selective neck dissection for patients with oral squamous cell carcinoma? EurArchOtorhinolaryngol. 2008;265(S1):13-7.
https://doi.org/10.1007/s00405-007-0465-z
Tanis PJ, Nieweg OE, van den Brekel MW, Balm AJ. Dilemma of clinically node-negative head and neck melanoma: outcome of ''Watch and wait'' policy, elective lymph node dissection, and sentinel node biopsy-a systematic review. Head Neck. 2008;30:380-9.
https://doi.org/10.1002/hed.20749
Gourin CG, Conger BT, Porubsky ES, Sheils WC, Bilodeau PA, Coleman TA. The effect of occult nodal metastases on survival and regional control in patients with head and neck squamous cell carcinoma. Laryngoscope. 2008;118(7):1191-4.
https://doi.org/10.1097/MLG.0b013e31816e2eb7
Quon H, O'Malley Jr BW, Weinstein GS. Transoral robotic surgery (TORS) for the head and neck: current and future indications. International journal head necksurg. 2010;1(3):133-40.
https://doi.org/10.5005/jp-journals-10001-1027
Laccourreye O, Hans S, Menard M, Garcia D, Brasnu D, Holsinger FC. Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region: II. An analysis of the incidence, related variables, and consenquences of local recurrence. Archotol head necksurg. 2005;131(7):592-9.
How to Cite
Downloads
Downloads
Published
Issue
Section
License
Todos los derechos reservados.
