Retroperitoneal tumors: 11 years experience in a cancer reference center in a Latin-American country (2000-2011)
Keywords:
Retroperitoneal space, Sarcoma, Neoplasms, SurgeryAbstract
Objective: To describe the clinical-pathological features, postoperative and oncological outcomes of patients diagnosed with retroperitoneal soft tissue tumors operated at the National Cancer Institute (NCI), over a period of 11 years.
Methods: A retrospective and descriptive study was performed that included patients operated in the NCI between years 2000 and 2011.
Results: In total there were 101 patients. The median age was 52 years, with 56.4% of them women. Among the operated patients, 60.4% had primary disease, 23.8% recurrent disease, and 15.8% (n = 16) were submitted as unresectable.
The main method of imaging was abdominal helical double-contrast tomography (89.1%). The most common histological type was well differentiated liposarcoma. Complete resection was achieved in 74.3%, with en bloc resections of involved structures in 68.3% of patients. Intraoperative complications occurred in 55.4% of patients, the most frequent being bleeding. Median follow-up was 549 days, with an overall survival of 41.1% at 5 years. Local recurrence was 54.2% and the systemic progression was 25%.
Conclusion: Retroperitoneal tumors are rare tumors that are usually diagnosed in advanced stages. They have a poor prognosis, mainly due to a high rate of local relapse. The mainstay of optimal management is surgery, and starts from the suspected diagnosis, encompassing the rational use of images, histological analysis by experienced pathologists, preoperative planning, and the decision of neoadjuvant or adjuvant therapies according to the type and tumor stage.
Author Biographies
Mauricio García, Instituto Nacional de Cancerología
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Carlos Lehmann, Instituto Nacional de Cancerología
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Diana Ríos, Instituto Nacional de Cancerología
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Posgrado Mastología, Fundación Universitaria de Ciencias de la Salud, Bogotá, D. C., Colombia
Nubia Prada, Instituto Nacional de Cancerología
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Posgrado Mastología, Fundación Universitaria de Ciencias de la Salud, Bogotá, D. C., Colombia
Héctor López, Instituto Nacional de Cancerología
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Posgrado Cirugía Oncológica, Universidad Militar Nueva Granada, Bogotá , D. C., Colombia
Sandra Díaz, Instituto Nacional de Cancerología
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Javier Ángel, Instituto Nacional de Cancerología
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Oscar García, Instituto Nacional de Cancerología, Bogotá
Clínica de Seno y Tejidos Blandos, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
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