Survival in patients with brain metastases treated with whole-brain radiotherapy
Keywords:
Cancer, Brain metastases, Radiotherapy, SurvivalAbstract
Objective: To describe the overall survival in patients with cerebral metastases treated with holocraneal radiotherapy in the period 2015-2016 in the Dr. Teodoro Maldonado Carbo hospital in the city of Guayaquil.
Methods: An observational longitudinal study was conducted on a sample of 48 patients. The Kaplan-Meier curve was used and the results were corroborated with non-parametric tests. Results: The overall median survival was 5.8 months, and the factors that indicated a longer survival time were: age less than 65 years, Karnofsky index greater or equal to 70, primary tumour control, metastases from the breast, class 1 of the recursive partitioning analysis (RPA), and a score of 3.5-4 in the graded prognostic assessment (GPA). The median survival of the primary tumour is also described, with the highest being 10.3 months and the lowest 0.5 months in those of the breast and cervix, respectively.
Conclusion: The median survival of patients in this study, according to the RPA scale, was higher than that reported in the literature for all patients. The median survival, according to the GPA score, was lower in patients with a 0-1 score, and higher in the remainder.
Author Biography
Jorge Ávila, Universidad de Especialidades Espíritu Santo
Facultad de Ciencias Médicas, Universidad de Especialidades Espíritu Santo, Guayaquil, Ecuador
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