Neuroendocrine rectal carcinoma: An infrequent tumour
Keywords:
Neuroendocrine carcinoma, Drug therapy, Rectal tumoursAbstract
Neuroendocrine carcinoma (NC) is an infrequent pathology that is usually found in the advanced stages. The treatment is surgery, and combined chemotherapy andradiotherapy. A 73-yearold woman was being studied for constitutional syndrome and rectal bleeding. After which, she was diagnosed with a poorly differentiated rectal NC, 5 cm from de anal margin with mesorectal lymph nodes. Induction chemotheraphy was started with partial response.
A low anterior resection of rectum was performed with primary anastomoses and diverting loop ileostomy. The histology result was a large-cell NC, staged as pT2N0 Mx. She then received adjuvant chemotherapy. Rectal NC is infrequent, and usually presents between the fourth and seventh decade of life. Its symptoms are similar to colorectal adenocarcinoma, but it has a lower grade of differentiation, and is more aggressive. Neoadjuvant treatment is essential as it usually a metastatic disease at diagnosis, and helps to decrease the tumour size, and and allows oncological surgery to be performed later.
Author Biographies
Eduardo Pérez-Sánchez, Hospital Universitario Nuestra Señora de Candelaria
Unidad de Coloproctología, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, España
Moisés Hernández-Barroso, Hospital Universitario Nuestra Señora de Candelaria
Unidad de Coloproctología, Servicio de Cirugía General y del Aparato Digestivo,Hospital Universitario Nuestra Señora de Candelaria, Tenerife, España
Guillermo Hernández-Hernández, Hospital Universitario Nuestra Señora de Candelaria
Unidad de Coloproctología, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, España
Luisa Gambra-Michel, Hospital Universitario Nuestra Señora de Candelaria
Unidad de Coloproctología, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, España
Manuel Barrera-Gómez, Hospital Universitario Nuestra Señora de Candelaria
Unidad de Coloproctología, Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, España
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