Cancer and pregnancy: Six years of experience in a cancer reference centre in a Latin-American country (2007-2013)
Keywords:
Pregnancy, Neoplasms, Case reportsAbstract
Objective: To describe the socio-demographic, epidemiological, clinical and pathological characteristics, as well as the treatment and complications of patients diagnosed with cancer who became pregnant and those that were diagnosed with cancer when pregnant.
Methods: Case series study. Patients treated in the National Cancer Institute (Bogotá, Colombia) from August 2007 to July 2013. The epidemiological, clinical, treatment, and complications were reviewed in the medical records. Adherence treatment was recorded. A descriptive data analysis was performed.
Results: The study included 38 patients, of whom 28 already had a cancer diagnosis. The main diagnosis was cervical cancer. The median gestational age at the end of pregnancy was 35 weeks (interquartile range 12 weeks). The main route was vaginal birth (60%), followed by caesarean section (40%). Treatment had to be suspended in 55.5% of cases, 38.9% had changes, and the therapeutic dose was modified in 5.6%. The complications presented during pregnancy were preterm birth, abortions, bleeding, stillbirths, oligohydramnios, and anaemia. A description is presented of the cases of patients who were diagnosed with neoplastic disease during their pregnancy. Adherence to treatment was good in 26 patients and not good in 8 cases.
Conclusions: The patient with cancer and pregnancy represents a diagnostic and therapeutic challenge to the obstetrician and the oncology group. Counselling on contraception and sexual and reproductive health should be emphasised.
Author Biographies
Jesús Acosta, Instituto Nacional de Cancerología
Grupo de Ginecología Oncológica, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
Oscar Serrano, Instituto Nacional de Cancerología
Grupo de Ginecología Oncológica, Instituto Nacional de Cancerología, Posgrado de Ginecología Oncológica, Universidad Militar Nueva Granada, Bogotá, D. C., Colombia
Lina Trujillo, Instituto Nacional de Cancerología
Grupo de Ginecología Oncológica, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
David Morales, Instituto Nacional de Cancerología
Grupo de Ginecología Oncológica, Instituto Nacional de Cancerología,Posgrado de Ginecología Oncológica, Universidad Militar Nueva Granada, Bogotá, D. C., Colombia
David López, Instituto Nacional de Cancerología
Grupo de Investigación Clínica, Instituto Nacional de Cancerología, Bogotá, D. C., Colombia
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