Tumour recurrence after cryosurgery in the treatment of low risk basal cell carcinoma
Keywords:
Basal cell carcinoma, Cryosurgery, Therapeutics, Skin neoplasmsAbstract
Objectives: The objective of this study is to describe the demographic, clinical and histological characteristics of the population studied, and to determine the recurrence or cure rate of low-risk basal cell carcinoma treated with cryosurgery.
Methods: A retrospective study was conducted on a case series of patients with low-risk basal cell carcinoma treated with cryosurgery between January 2009 and August 2012, in the Dermatology Department of the National Institute of Cancerology (Bogotá, Colombia). The clinical follow-up ranged between 1.7 months and 64.3 months. Each tumour was treated with a standardised cryosurgery procedure performed by the same operator. In each case, the tumour margins were delineated with careful dermoscopic evaluation. Saucerisation was performed in case of clinical visible tumour. Two freeze-thaw spray cycles were performed. Progression free survival was measured using the Kaplan - Meier method.
Results: In the analysis of 108 patients with 156 tumours, there was a clinical cure-rate of 98.7% of tumours. Two tumour recurrences located in the H area were detected at 17 months and 22 months after treatment in two male patients.
Conclusion: Data from clinical cure-rate reported in the literature were similar to our study. In this group of patients, it was shown that in low-risk basal cell carcinoma treated with cryosurgery, the cure-rates were equivalent to those described in the literature with surgical
resection.
Author Biographies
Ana Martínez, Instituto Nacional de Cancerología
Grupo Dermatología Oncológica, Instituto Nacional de Cancerología, Bogotá, D.C., Colombia
Álvaro Acosta, Instituto Nacional de Cancerología
Grupo Dermatología Oncológica, Instituto Nacional de Cancerología, Bogotá, D.C., Colombia
Xavier Rueda, Instituto Nacional de Cancerología
Grupo Dermatología Oncológica, Instituto Nacional de Cancerología, Bogotá, D.C., Colombia
David López-Daza, Instituto Nacional de Cancerología
Grupo de Investigación Clínica, Instituto Nacional de Cancerología, Bogotá, D.C., Colombia
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