Primary breast squamous metaplastic squamous cell carcinoma: of the breast: a rare subtype. Presentation of three cases in the Hospital Universitario del Caribe
Keywords:
Metaplastic breast carcinoma, Squamous cell carcinoma of the breast, Breast carcinomaAbstract
Ductal carcinomas are the most common of all breast malignancies, less than 5% are of metaplastic nature, and 0.04% to 0.1% have squamous cell differentiation. These special subtypes are considered more aggressive. Due to the few cases in the literature, there is no consensus about its diagnosis and treatment. Three cases are presented with this diagnosis, seen in our institution between 2014 and 2015. They were women of 57, 49, and 65 years old with no risk factors, and who presented with similar clinical features, consisting of the appearance of a rapid growing mass. Two of the patients had been previously diagnosed with infiltrating ductal carcinoma of no special type by core needle biopsy, with a definitive diagnosis in radical mastectomy, which reported squamous metaplastic carcinoma confirmed by immunohistochemistry.
Author Biographies
Saúl Andrés Rivero Monterrosa, Universidad de Cartagena
Posgrado de Patología, Facultad de Medicina, Universidad de Cartagena, Cartagena de Indias, Bolívar, Colombia
Karoll D Robles Pérez, Universidad de Cartagena
Posgrado de Patología, Facultad de Medicina, Universidad de Cartagena, Cartagena de Indias, Bolívar, Colombia
Olivia Marrugo Grice, Universidad de Cartagena
Departamento de Patología, Facultad de Medicina, Universidad de Cartagena, Cartagena de Indias, Bolívar, Colombia
César Redondo Bermúdez, Universidad de Cartagena
Departamento de Patología, Facultad de Medicina, Universidad de Cartagena, Cartagena de Indias, Bolívar, Colombia
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