Focal thrombosis of common femoral vein: initial manifestation of diffuse large B cell lymphoma

Authors

  • Ruth Fuente Hospital Clínico Universitario de Valladolid
  • Diana Gutiérrez Hospital Clínico Universitario de Valladolid
  • Miguel Martín Pedrosa Hospital Clínico Universitario de Valladolid
  • Cintia Flota Hospital Clínico Universitario de Valladolid
  • Carlos Vaquero Hospital Clínico Universitario de Valladolid

DOI:

https://doi.org/10.35509/01239015.174

Keywords:

Deep venous thrombosis, Extrinsic compression, Non-Hodgkin lymphoma

Abstract

Deep venous thrombosis (DVT) is a common disease that annually affects 0.1-0.3%of the general population; It is also a significant cause of morbidity and mortality in cancerpatients. DVT occurs more frequently in the treatment phase in which they are associated withthe neoplastic prothrombotic process and effects of chemotherapy. In a small number of cases itis identified in the diagnosis or it may even be its first symptom. A secondary focal DVT extrinsiccompression and destruction of surrounding tissue raises the suspicion of a malignant process.A case is presented of a focal DVT that was the first manifestation a non-Hodgkin’s diffuse largeB-cell lymphoma.

Author Biographies

Ruth Fuente, Hospital Clínico Universitario de Valladolid

Servicio de Angiología y Cirugía Vascular, Hospital Clínico Universitario de Valladolid, España

Diana Gutiérrez, Hospital Clínico Universitario de Valladolid

Servicio de Angiología y Cirugía Vascular, Hospital Clínico Universitario de Valladolid, España

Miguel Martín Pedrosa, Hospital Clínico Universitario de Valladolid

Servicio de Angiología y Cirugía Vascular, Hospital Clínico Universitario de Valladolid, España

Cintia Flota, Hospital Clínico Universitario de Valladolid

Servicio de Angiología y Cirugía Vascular, Hospital Clínico Universitario de Valladolid, España

Carlos Vaquero, Hospital Clínico Universitario de Valladolid

Servicio de Angiología y Cirugía Vascular, Hospital Clínico Universitario de Valladolid, España

References

Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H. World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2008.

Sant M, Allemani C, Tereanu C, De Angelis R, Capocaccia R, Visser O, et al. Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project. Blood. 2010;116:3724-34.

https://doi.org/10.1182/blood-2010-05-282632

Hui D, Proctor B, Donaldson J, Shenkier T, Hoskins P, Klasa R, et al. Prognostic implications of extranodal involvement in patients with diffuse large B-cell lymphoma treated with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone. Leuk Lymphoma. 2010;51:1658-67.

https://doi.org/10.3109/10428194.2010.504872

Armitage JO, Weisenburger DD. New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's Lymphoma Classification Project. J Clin Oncol. 1998;16:2780-95.

https://doi.org/10.1200/JCO.1998.16.8.2780

Falanga A, Donati MB. Pathogenesis of thrombosis in patients with malignancy. Int J Hematol. 2001;73:137-44.

https://doi.org/10.1007/BF02981929

Korte W. Cancer and thrombosis: an increasingly important association. Support Care Cancer. 2008;16:223-8.

https://doi.org/10.1007/s00520-007-0376-y

Caruso V, Iacoviello L, Di Castelnuovo A, Storti S, Mariani G, de Gaetano G, et al. Thrombotic complications in childhoodacute lym-phoblastic leukemia: a meta-analysis of 17 prospective studies comprising 1752 paediatric patients. Blood. 2006;108:2216-22.

https://doi.org/10.1182/blood-2006-04-015511

Caruso V, Iacoviello L, Di Castelnuovo A, Storti S, Donati MB. Venous thrombotic complications in adults undergoing induction treatment for acute lymphoblastic leukemia: results from a meta-analysis. J Thromb Haemost. 2007;5:621-3.

https://doi.org/10.1111/j.1538-7836.2007.02383.x

Kwaan HC, Vicuna B. Incidence and pathogenesis of thrombosis in hematologic malignancies. Semin Thromb Hemost. 2007;33:303-12.

https://doi.org/10.1055/s-2007-976164

Caruso V, Di Castelnuovo A, Meschengieser S, Lazzari M, de Gaetano G, Storti S, et al. Thrombotic complications in adult patients with lymphoma: a meta-analysis of 29 independent cohorts including 18018 patients and 1149 events. Blood. 2010;115:5322-8.

https://doi.org/10.1182/blood-2010-01-258624

How to Cite

[1]
Fuente, R. et al. 2018. Focal thrombosis of common femoral vein: initial manifestation of diffuse large B cell lymphoma. Revista Colombiana de Cancerología. 22, 1 (Mar. 2018), 53–56. DOI:https://doi.org/10.35509/01239015.174.

Downloads

Download data is not yet available.

Published

2018-03-01

Issue

Section

Reportes de caso
Crossref Cited-by logo