Acute pancreatitis in small-cell lung carcinoma (SCLC) resolved with chemotherapy
DOI:
https://doi.org/10.35509/01239015.15Keywords:
Acute pancreatitis, Small cell lung carcinomaAbstract
Small cell lung cancer is a subtype of neoplasm that has typically been associated with smoking and is characterized by its aggressiveness and poor prognosis in the short term. As an entity it can metastasize in any organ, but pancreatic metastases are rare and most of the time asymptomatic. Therefore, the presence of neoplastic pancreatitis as in our case is exceptional and even more so when it presents refractoriness to conventional medical treatment, responding instead to systemic cytotoxic treatment. Therefore, we expose our clinical experience and discuss the presence of this rare entity and its management.
References
Yeung K, Haidak DJ, Brown JA, Anderson D. Metastasis- induced acute pancreatitis in small cell bronchogenic carcinoma. Arch Intern Med. 1979;139(5):552-4. https://doi. org/10.1001/archinte.1979.03630420042014
Tejedor-Bravo M, Justo LM, Lasala JP, Moreira-Vicente VF, Cano- Ruiz A, Martín-Scapa Mde L. Acute pancreatitis secondary to neuroendocrine pancreatic tumors. Pancreas. 2012;41(3):485-9. https://doi.org/10.1097/MPA.0b013e318227adef
Gonlugur U, Mirici A, Karaayvaz M. Pancreatic involvement in small cell lung cancer. Radiol Oncol. 2014;48(1):11-9. https://doi.org/10.2478/raon-2013-0022
Belhassen-García M, Velasco-Tirado V, Carpio-Pérez A, Soler- Fernández MC, López-Bernús A, Pardo-Lledias J, et al. [Acute pancreatitis and obstructive jaundice secondary to metastases from lung cáncer]. Gastroenterol Hepatol. 2009;32(10):697- 701. https://doi.org/10.1016/j.gastrohep.2009.07.013
Kim KH, Kim CD, Lee SJ, Lee G, Jeen YT, Lee HS, et al. Metastasis-induced acute pancreatitis in a patient with small cell carcinoma of the lung. J Korean Med Sci. 1999;14(1):107- 9. https://doi.org/10.3346/jkms.1999.14.1.107
García Bennett J, Sabaté Fernández M. [Acute pancreatitis as an initial symptom of a small-cell carcinoma of the lung]. Radiologia. 2015;57(1):81-2. https://doi.org/10.1016/j. rx.2013.04.004
Yamanashi K, Marumo S, Saitoh M, Kato M. A case of metastasis-induced acute pancreatitis in a patient with small cell lung cancer. Clin Case Rep. 2015;3(2):96-8. https://doi. org/10.1002/ccr3.163
Roth BJ, Johnson DH, Einhorn LH, Schacter LP, Cherng NC, Cohen HJ, et al. Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small- cell lung cancer: a phase III trial of the Southeastern Cancer Study Group. J Clin Oncol. 1992;10(2):282-91. https://doi. org/10.1200/JCO.1992.10.2.282
Fukuoka M, Furuse K, Saijo N, Nishiwaki Y, Ikegami H, Tamura T, et al. Randomized trial of cyclophosphamide, doxorubicin, and vincristine versus cisplatin and etoposide versus alternation of these regimens in small-cell lung cancer. J Natl Cancer Inst. 1991;83(12):855-61. https://doi.org/10.1093/ jnci/83.12.855
Sundstrøm S, Bremnes RM, Kaasa S, Aasebø U, Hatlevoll R, Dahle R, et al. Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years’ follow-up. J Clin Oncol. 2002;20(24):4665- 72. https://doi.org/10.1200/JCO.2002.12.111
Horn L, Mansfield AS, Szczesna A, Havel L, Krzakowski M, Hochmair MJ, et al. First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer. N Engl J Med. 2018;379(23):2220-9. https://doi.org/10.1056/ NEJMoa1809064
Antonia SJ, López-Martin JA, Bendell J, Ott PA, Taylor M, Eder JP, et al. Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial. Lancet Oncol. 2016;17(7):883-95. https://doi.org/10.1016/S1470-2045(16)30098-5
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