Childhood Wilms tumor, relapsed more than 20 years after diagnosis
Keywords:
Wilms tumor, kidney neoplasms, drug therapy, combination, second look surgery, recurrenceAbstract
Wilms tumor represents the most common renal neoplasm in childhood; however, in adulthood, it is a rare condition, and the optimal management is unknown. Treatments are usually extrapolated from the multimodal approach used in the pediatric population.
We present the case of a 29-year-old female patient with a history of stage III right-sided Wilms tumor (favorable classification) at the age of 4, managed with surgery, chemotherapy, and radiotherapy. More than 20 years later, recurrent Wilms tumor was confirmed in the peritoneum and both ovaries and treated with ICE (ifosfamide, carboplatin, and etoposide) chemotherapy regimen, leading to severe toxicity but a good response. The patient underwent salvage surgery with complete resection. Eventually, she presented new relapses managed with chemotherapy.
Author Biographies
Alicia Quiroga-Echeverri, Oncología Clínica, Unidad de Cancerología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
1. Oncología Clínica, Unidad de Cancerología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
Luis Gabriel González-Pérez, Oncología Clínica, Unidad de Cancerología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
1. Oncología Clínica, Unidad de Cancerología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
Juan Fernando Arango-Arteaga, Oncología Clínica, Unidad de Cancerología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
1. Oncología Clínica, Unidad de Cancerología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
Ana María Arango-Rivas , Medicina Interna, Clínica AUNA, Medellín, Colombia.
2. Medicina Interna, Clínica AUNA, Medellín, Colombia.
Gabriel Jaime Varela-Aguirre , Hospital Pablo Tobón Uribe, Medellín, Colombia.
3. Hospital Pablo Tobón Uribe, Medellín, Colombia.
4. Clínica Aurora, Medellín, Colombia.
5. Hospital San Vicente Fundación, Rionegro, Colombia.
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