Large cell lymphoma in children and adolescents of the Instituto Nacional de Cancerología E.S.E.: (Bogotá, D.C., Colombia): 1980-2001

Authors

  • Iliana de los Reyes Instituto Nacional de Cancerología
  • Teresa Martínez Instituto Nacional de Cancerología
  • Martha Vizcaíno Instituto Nacional de Cancerología
  • Carlos Moreno Instituto Nacional de Cancerología

Keywords:

Lymphoma, large cell, survival rate, child, adolescent, Colombia
Abstract Authors References How to Cite

Abstract

Objective: To characterize and establish the survival of pediatric patients with lymphoma treated at the National Cancer Institute of Colombia during the period 1980-2001.
Methods: Clinical records of nineteen patients were reviewed, diagnosis was confirmed by morphology, and immune-phenotype was established with CD20, CD30, CD43, CD45RB, CD45RO, CD68, CD3, ALK, tdt and S-100 antibodies. Associations were established by using Fischer’s exact test, Kaplan-Meier’s method for survival, and the log rank test to compare survival trends.
Results: Ten patients were girls; the age median was eleven years, with a range between three and sixteen years. Seven cases presented lymphoma at the neck, which was the most frequent localization. Nine patients were at stage I; the most frequent immune-phenotype was that of T cells, with eleven cases. Thirteen patients presented complete remission. After two years, event-free survival was 47.3%, diseasefree survival was 99.8%, and global survival 68%. After five years, event-free survival was 28,8%.
Conclusion: A bigger number of patients must be studied in order to establish more precise estimations concerning clinical features and survival.

Author Biographies

Iliana de los Reyes, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología E.S.E., Grupo Oncología Pediátrica, Bogotá, D.C., Colombia.

Teresa Martínez, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología E.S.E., Grupo Epidemiología Clínica, Bogotá, D.C., Colombia.

Martha Vizcaíno, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología E.S.E., Grupo Oncología Pediátrica, Bogotá, D.C., Colombia.

Carlos Moreno, Instituto Nacional de Cancerología

Especialista en Hematopatología, Instituto Nacional de Cancerología E.S.E., Bogotá, D.C., Colombia.

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How to Cite

[1]
de los Reyes, I. et al. 2005. Large cell lymphoma in children and adolescents of the Instituto Nacional de Cancerología E.S.E.: (Bogotá, D.C., Colombia): 1980-2001. Revista Colombiana de Cancerología. 9, 1 (Mar. 2005), 19–28.

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Published

2005-03-01

Issue

Vol. 9 No. 1 (2005)

Section

Research/original articles

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