Systemic mastocytosis with polyostotic bone involvement
Keywords:
Systemic mastocytosis, radiography, bone and bones, abnormalities, skinAbstract
Mastocytosis is a heterogeneous group of diseases characterized by the proliferation of mast cells and their subsequent accumulation in one or more organ systems. The signs and symptoms of the mast cell disease are varied, depending on the localization of the mast cell in different organs and on the local and systemic effects of the mediators released by these cells. Cutaneous mast cell disease is the most common one, either localized in the skin or associated with extracutaneous organs. Most patients have a favourable outcome: their lesions regress spontaneously, remain stable, or are only slowly progressive. In others, the mast cell proliferation is systemic, with or without evidence of skin infiltration. Mast cell leukemia, mast cell sarcoma, and hematological malignancy are rare. The case considered in this paper is a 52-year-old man’s with multiple lytic osseous lesions due to a systemic mastocytosis.
Author Biographies
Patricia Meléndez, Instituto Nacional de Cancerología
Instituto Nacional de Cancerología, E.S.E., Grupo de imágenes radiodiagnósticas, Bogotá, D.C., Colombia.
Elvira Castro
Patóloga Oncóloga, Bogotá, D.C., Colombia.
Fabián Neira, Instituto Nacional de Cancerología
Instituto Nacional de Cancerología, E.S.E., Grupo de imágenes radiodiagnósticas, Bogotá, D.C., Colombia.
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