Nesidioblastosis del adulto coexistente con insulinoma

Autores/as

  • Katherine Restrepo Instituto Nacional de Cancerología
  • Gloria Garavito Instituto Nacional de Cancerología
  • Leonardo Rojas Instituto Nacional de Cancerología
  • Alfredo Romero Instituto Nacional de Cancerología
  • Fabián Neira Instituto Nacional de Cancerología
  • Ricardo Oliveros Instituto Nacional de Cancerología
  • Nadin Abisambra

Palabras clave:

Hipoglucemia, hiperinsulinismo, nesidioblastosis, insulinoma, adulto

Resumen

La nesidioblastosis es poco común, pero ampliamente reconocida como causa de la hipoglucemia hiperinsulinémica persistente de la infancia. En adultos, el insulinoma es la principal causa de hipoglucemia hiperinsulinémica, pero también se han identificado casos de nesidioblastosis, los cuales se denominan ‘síndrome de hipoglucemia pancreatógena no insulinoma’. Los primeros casos de nesidioblastosis del adulto que fueron descritos se asociaron con otras condiciones, como insulinoma y tumores neuroendocrinos pancreáticos y MEN-1. En este artículo se describe un caso de nesidioblastosis coexistente con insulinoma en una paciente de 20 años; se hace una revisión de la literatura; se plantea la discusión sobre su posible etiología, presentación clínica, diagnóstico, tratamiento y, finalmente, se presenta un algoritmo para su estudio.

Biografía del autor/a

Katherine Restrepo, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología, Bogotá, Colombia.

Gloria Garavito, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología, Bogotá, Colombia.

Leonardo Rojas, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología, Bogotá, Colombia.

Alfredo Romero, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología, Bogotá, Colombia.
Universidad Nacional de Colombia, Bogotá, Colombia.

Fabián Neira, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología, Bogotá, Colombia.
Universidad Nacional de Colombia, Bogotá, Colombia.

Ricardo Oliveros, Instituto Nacional de Cancerología

Instituto Nacional de Cancerología, Bogotá, Colombia.
Universidad Nacional de Colombia, Bogotá, Colombia.

Nadin Abisambra

Instituto Nacional de Cancerología, Bogotá, Colombia.
Universidad Nacional de Colombia, Bogotá, Colombia.

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Cómo citar

[1]
Restrepo, K. et al. 2009. Nesidioblastosis del adulto coexistente con insulinoma. Revista Colombiana de Cancerología. 13, 1 (mar. 2009), 49–60.

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